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A new extended half-life rFVIII hemophilia A treatment with a unique, step-wise prophylaxis dosing regimen1

For hemophilia A patients 12 years and older

  • The recommended initial regimen is 30–40 IU/kg twice weekly.
  • Based on the bleeding episodes:
    • The regimen may be adjusted to 45–60 IU/kg every 5 days.
    • A regimen may be further individually adjusted to less or more frequent dosing.

IU, international units; kg, kilograms; rFVIII, recombinant Factor VIII.